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KMID : 1148420210040020052
Journal of Neurointensive Care
2021 Volume.4 No. 2 p.52 ~ p.57
Clinical Outcomes of Cranioplasty Using a Customized Artificial Bone Flap Made by a 3D Printing Technique
Lee Jin-Ho

Shim Yong-Woo
Kim Sung-Tae
Lee Won-Hee
Lee Keun-Soo
Paeng Sung-Hwa
Pyo Se-Young
Abstract
Objective: To analyze the outcomes of using a customized artificial skull bone flap made with a three-dimensional (3D) printing technique for cranioplasty and compare them with those of the autobone technique.

Method: Between December 2018 and February 2020, 24 cranioplasties were performed for 24 hemispheres using a customized artificial bone flap made by 3D printing. Simultaneously, 19 cranioplasties for 19 hemispheres were performed using an autobone. Three patients underwent cranioplasty using both a customized artificial bone flap and autobone for each hemisphere. Patient¡¯s demographics, reason for craniectomy, interval between craniectomy and cranioplasty, surface area of the skull defect and bone flap, bone flap coverage of the defect, cranioplasty-related factors, and clinical outcome were assessed.

Results: Forty patients who underwent cranioplasty (bone flap, 21; autobone flap, 16; and artificial bone/autobone flaps, 3) were enrolled. The artificial bone flap covered more skull defects than the autobone flap (98.6% vs. 90.9%, p=0.000). There were two and six operation-related complications in the artificial bone flap and autobone flap groups, respectively (P=0.061). The subtemporal area was completely covered in the artificial bone flap group. Two patients had an infection of the autobone flap and had it replaced by a 3D printing flap. No patient showed a reduction in the modified Rankin Scale score after surgery, and the clinical course was confirmed to have improved.

Conclusion: Cranioplasty using customized artificial bone flap made by 3D printing technique was effective for covering the skull defect and tends to have a low complication rate compared to the autobone.
KEYWORD
Autobone, Bone flap, Cranioplasty, Craniotomy, Printing, Three-dimensional
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